Therapeutic agents
Commercially available drugs/clinical diagnostic kits from snake venoms
| Drug/trade name | Target and treatment | Family/Species |
|---|---|---|
| Captopril; enalapril | ACE inhibitor/high blood pressure | Bothrops jaracusa (Brazilian arrowhead viper) |
| Integrilin (eptifibatide) | Platelet aggregation inhibitor, acute coronary syndrome | Sisturus miliarus barbouri (South-eastern pigmy rattlesnake) |
| Aggrastat (tirofiban) | GPIIb-IIIa inhibitor, myocardial infarct, refractory ischaemia | Echis carinatus (African saw-scaled viper) |
| Ancrod (Viprinex) | Fibrinogen inhibitor, stroke | Agkistrodon rhodostoma (Malayan pit viper) |
| Defibrase | Thrombin and Prothrombin inhibitor, acute cerebral infarction, unspecific angina pectoris | Bothrops moojeni |
| Hemocoagulase | Thrombin-like effect and thromboplastin activity, prevention and treatment of haemorrhage | Bothrops atrox |
| Protac/protein C activator protein C activator | Clinical diagnosis of haemostatic disorder | Agkistrodon contortix contortix (American copperhead) |
| Reptilase | Diagnosis of blood coagulation disorder | Bothrops jaraca (South American lance adder) |
| Ecarin | Prothrombin activator diagnostic | E. carinatus |
| Exanta; ximelagatran | Blood thinner, anti coagulant, thrombin inhibitor | Cobra |
| Eptifibatide | Antiplatelet drug | Derivatives of disintegrin from sistrurus miliarus barbouri |
| Tirofiban | Antiplatelet drug | Derivatives of disintegrin from Echis carinatus |
| Batroxobin | Defibrinogenating agent | Serine protease from Bothrops atrox and B. moojeni |
| Dendroaspis-NP | Congestive cardiac failure treatment | Natriuretic peptide from Dendroaspis angusticeps |
| α-Cobrotoxin/α-cobratoxin | Analysis | Neurotoxins from Naja nivea and Naja Kaouthia, respectively |